The emerging novel Middle East respiratory syndrome coronavirus: The “knowns” and “unknowns”
Identifieur interne : 001838 ( Main/Exploration ); précédent : 001837; suivant : 001839The emerging novel Middle East respiratory syndrome coronavirus: The “knowns” and “unknowns”
Auteurs : Jasper Fuk-Woo Chan [République populaire de Chine] ; Susanna Kar-Pui Lau [République populaire de Chine] ; Patrick Chiu-Yat Woo [République populaire de Chine]Source :
- Journal of the Formosan Medical Association [ 0929-6646 ] ; 2013.
Descripteurs français
- KwdFr :
- Animaux, Chiroptera (virologie), Coronaviridae, Découverte de médicament, Humains, Infections à Coronaviridae (diagnostic), Infections à Coronaviridae (traitement médicamenteux), Infections à Coronaviridae (transmission), Infections à Coronaviridae (virologie), Infections à Coronaviridae (épidémiologie), Moyen Orient (épidémiologie), Réservoirs d'agents pathogènes (virologie), Syndrome respiratoire aigu sévère (traitement médicamenteux), Syndrome respiratoire aigu sévère (virologie), Syndrome respiratoire aigu sévère (épidémiologie).
- MESH :
- diagnostic : Infections à Coronaviridae.
- traitement médicamenteux : Infections à Coronaviridae, Syndrome respiratoire aigu sévère.
- virologie : Chiroptera, Infections à Coronaviridae, Réservoirs d'agents pathogènes, Syndrome respiratoire aigu sévère.
- épidémiologie : Infections à Coronaviridae, Moyen Orient, Syndrome respiratoire aigu sévère.
- Animaux, Coronaviridae, Découverte de médicament, Humains.
English descriptors
- KwdEn :
- Animals, Chiroptera (virology), Coronaviridae, Coronaviridae Infections (diagnosis), Coronaviridae Infections (drug therapy), Coronaviridae Infections (epidemiology), Coronaviridae Infections (transmission), Coronaviridae Infections (virology), Disease Reservoirs (virology), Drug Discovery, Humans, Middle East (epidemiology), Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (virology).
- MESH :
- geographic , epidemiology : Middle East.
- diagnosis : Coronaviridae Infections.
- drug therapy : Coronaviridae Infections, Severe Acute Respiratory Syndrome.
- epidemiology : Coronaviridae Infections, Severe Acute Respiratory Syndrome.
- transmission : Coronaviridae Infections.
- virology : Chiroptera, Coronaviridae Infections, Disease Reservoirs, Severe Acute Respiratory Syndrome.
- Animals, Coronaviridae, Drug Discovery, Humans.
Abstract
A novel lineage C betacoronavirus, originally named human coronavirus EMC/2012 (HCoV-EMC) and recently renamed Middle East respiratory syndrome coronavirus (MERS-CoV), that is phylogenetically closely related to
Url:
DOI: 10.1016/j.jfma.2013.05.010
PubMed: 23883791
PubMed Central: 7125600
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>A novel lineage C betacoronavirus, originally named human coronavirus EMC/2012 (HCoV-EMC) and recently renamed Middle East respiratory syndrome coronavirus (MERS-CoV), that is phylogenetically closely related to <italic>Tylonycteris</italic>
bat coronavirus HKU4 and <italic>Pipistrellus</italic>
bat coronavirus HKU5, which we discovered in 2007 from bats in Hong Kong, has recently emerged in the Middle East to cause a severe acute respiratory syndrome (SARS)-like infection in humans. The first laboratory-confirmed case, which involved a 60-year-old man from Bisha, the Kingdom of Saudi Arabia (KSA), who died of rapidly progressive community-acquired pneumonia and acute renal failure, was announced by the World Health Organization (WHO) on September 23, 2012. Since then, a total of 70 cases, including 39 fatalities, have been reported in the Middle East and Europe. Recent clusters involving epidemiologically-linked household contacts and hospital contacts in the Middle East, Europe, and Africa strongly suggested possible human-to-human transmission. Clinical and laboratory research data generated in the past few months have provided new insights into the possible animal reservoirs, transmissibility, and virulence of MERS-CoV, and the optimal laboratory diagnostic options and potential antiviral targets for MERS-CoV-associated infection.</p>
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</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>République populaire de Chine</li>
</country>
</list>
<tree><country name="République populaire de Chine"><noRegion><name sortKey="Chan, Jasper Fuk Woo" sort="Chan, Jasper Fuk Woo" uniqKey="Chan J" first="Jasper Fuk-Woo" last="Chan">Jasper Fuk-Woo Chan</name>
</noRegion>
<name sortKey="Chan, Jasper Fuk Woo" sort="Chan, Jasper Fuk Woo" uniqKey="Chan J" first="Jasper Fuk-Woo" last="Chan">Jasper Fuk-Woo Chan</name>
<name sortKey="Chan, Jasper Fuk Woo" sort="Chan, Jasper Fuk Woo" uniqKey="Chan J" first="Jasper Fuk-Woo" last="Chan">Jasper Fuk-Woo Chan</name>
<name sortKey="Lau, Susanna Kar Pui" sort="Lau, Susanna Kar Pui" uniqKey="Lau S" first="Susanna Kar-Pui" last="Lau">Susanna Kar-Pui Lau</name>
<name sortKey="Lau, Susanna Kar Pui" sort="Lau, Susanna Kar Pui" uniqKey="Lau S" first="Susanna Kar-Pui" last="Lau">Susanna Kar-Pui Lau</name>
<name sortKey="Lau, Susanna Kar Pui" sort="Lau, Susanna Kar Pui" uniqKey="Lau S" first="Susanna Kar-Pui" last="Lau">Susanna Kar-Pui Lau</name>
<name sortKey="Woo, Patrick Chiu Yat" sort="Woo, Patrick Chiu Yat" uniqKey="Woo P" first="Patrick Chiu-Yat" last="Woo">Patrick Chiu-Yat Woo</name>
<name sortKey="Woo, Patrick Chiu Yat" sort="Woo, Patrick Chiu Yat" uniqKey="Woo P" first="Patrick Chiu-Yat" last="Woo">Patrick Chiu-Yat Woo</name>
<name sortKey="Woo, Patrick Chiu Yat" sort="Woo, Patrick Chiu Yat" uniqKey="Woo P" first="Patrick Chiu-Yat" last="Woo">Patrick Chiu-Yat Woo</name>
</country>
</tree>
</affiliations>
</record>
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